Significant research supports the cardiovascular benefits of L-arginine in promoting vascular health and blood flow. L-arginine enhances nitric oxide production in the arteries, which in turn relaxes blood vessels and maintains healthy blood flow. Perfusia Plus combines sustained-release L-arginine with nutritional cofactors that enhance nitric oxide synthesis in the blood vessels (5-MTHF and ascorbic acid), in addition to antioxidants and botanicals that promote normal blood flow (R-lipoic acid, green tea extract, and resveratrol).