Berberine is a natural plant alkaloid offering multiple health benefits*.Key nutritional features include maintaining already healthy cholesterol and blood sugar levels, promoting GI microbial balance, and supporting healthy metabolism*. Berberine Supplement Thorne Research is an alkaloid found in many plants, including Hydrastis canadensis (goldenseal), Coptis chinensis (Coptis or golden thread), Berberis aquifolium (Oregon grape), Berberis vulgaris (barberry), and Berberis aristata (Indian barberry). The berberine in Berbercap and Berberine-500 is from Indian barberry extract (root) (Berberis aristata).